Pesquisa sobre: HOMER SCAFFOLDING PROTEINS 
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Descritor Inglês:   Homer Scaffolding Proteins 
Descritor Espanhol:   Proteínas de Andamiaje Homer 
Descritor Português:   Proteínas de Arcabouço Homer 
Sinônimos Inglês:   Homer 1
Homer 1 Proteins
Homer 1C
Homer 1C Proteins
Homer 1a
Homer 2
Homer 2 Proteins
Homer 3
Homer 3 Proteins
Homer Proteins
Proteins, Homer
Proteins, Homer 1
Proteins, Homer 1C
Proteins, Homer 2
Proteins, Homer 3
Proteins, Homer Scaffolding
Scaffolding Proteins, Homer  
Categoria:   D12.776.476.024.381
Definição Inglês:   Homer proteins belong to a family of adaptor and scaffold proteins which include Homer1, Homer2 and Homer3. Homer1 and Homer2 play a role in the regulation of calcium homeostasis, whereas Homer3 functions in stimulating changes in actin dynamics in neurons and T-cells. Homer proteins are best known as scaffold proteins at the post-synaptic density where they facilitate synaptic signaling. They function as a molecular switch in metabotropic glutamate receptor (MGluR) signaling, and are associated with human Fragile X syndrome. 
Nota Histórica Inglês:   2017 (1997) 
Qualificadores Permitidos Inglês:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número do Registro:   56636 
Identificador Único:   D000072233 

Ocorrência na BVS:
 

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